Urea Cream 40% is a keratolytic emollient gentle, yet powerful, fabric softener for nails and / or skin. Each gram of urea cream, 40% and urea lotion, 40% contains 40% urea, purified water, mineral oil, petrolatum, propylene glycol, glycerol stearate, cetyl alcohol, carbomer, triethanolamine, and xanthan gum. Each gram of urea gel, 40% contains 40% urea, purified water, glycerin, PEG-6 caprylic / capric glycerides, hydroxethylcellulose, disodium EDTA, and xanthan gum. Urea diamide of carbonic acid with the following chemical structure:
Clinical pharmacology Urea Cream 40%:
Urea gently dissolves the intercellular matrix, which leads to a weakening of the stratum corneum of the skin and shedding scaly skin at regular intervals, thereby softening hyperkeratotic areas. Urea also hydrates and gently dissolves intercellular matrix of nail plate, which can lead to softening and eventual debridement of the nail plate.
Pharmacokinetics Urea Cream 40%:
Mechanism of action of topical application of urea is not yet known.
INDICATIONS AND USAGE Urea Cream 40%:
For debridement and promotion of normal healing of hyperkeratotic surface lesions, particularly in cases of local infection inhibited healing, necrotic tissue, fibrinous or lubricious debris or eschar. Urea is used for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, dry skin, ichthyosis, eczema, keratosis, keratoderma, corns and calluses, as well as damaged, ingrown nails and devitalized.
CONTRAINDICATIONS Urea Cream 40%:
Hypersensitivity to any of the listed ingredients.
WARNINGS:
For external use only. Avoid contact with eyes, lips and mucous membranes.
Precautions Urea Cream 40%:
This drug is to be used in accordance with the instructions of the physician and should not be used to treat any condition other than that for which it was prescribed. If redness or irritation, discontinue use.
REGNANCY Urea Cream 40%:
Pregnancy Category C. animal reproduction studies are not conducted with urea cream 40%. In addition, it is unknown whether UREA 40% cream may cause fetal harm when administered a pregnant woman or can affect reproduction capacity. UREA 40% should be given to pregnant women only if clearly needed.
NURSING MOTHERS Urea Cream 40%:
It is unknown whether this drug is released in human milk. Because many drugs are highlighted in human milk, caution should be exercised when urea cream 40% is administered to nursing mothers.
And keep it all medications out of reach of children.
Adverse reactions Urea Cream 40%:
Transient stinging, burning, itching or irritation may occur and typically disappear after discontinuation of the drug.
Dosage and administration Urea Cream 40%:
Apply cream UREA 40% of the affected skin twice daily or as directed by your doctor. Rub in until completely absorbed. Apply for a sick or damaged nail tissue twice per day, or as directed by your doctor.
